The Irish National Research Center for Advanced Materials and Bioengineering (AMBER) has collaborated with German scientists to develop a new type of biomaterial for tissue regeneration in patients with heart disease and burns. The research results were published in "Advanced Materials", an international authoritative journal of materials science. Â
For patients with nerve damage, it is currently very difficult to repair nerve damage of more than two centimeters. One possible method is to combine a regenerative biological material with a material that can perform electrical stimulation to transmit electrical signals through the damaged tissue, thereby restoring the affected area to function. Â
Collagen is very abundant in the human body and has regenerative potential. Graphene is the thinnest material in the world, with unique mechanical and electrical properties. The researchers combined the beneficial properties of the two materials and conducted a "biological hybridization" to produce a material with high mechanical strength and good electrical conductivity. This new material has been shown to promote cell growth. When electrical stimulation occurs, the cardiomyocytes can be adjusted according to the direction of the electrical pulse. This feature can be used to repair large-scale nerve defects and large-scale heart wall injuries, and can also be used to regenerate areas such as the spinal cord and brain. Â Â
In addition, this material has an anti-infection function and can be applied to the development of next-generation antimicrobial medical devices and biosensors. The AMBER center has also developed a low-cost mass production technology for graphene, which has created conditions for the large-scale application of this new biomaterial.
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